do a number on

To really hurt or damage something.

"The stress of the last year really did a number on her health."

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Artemis II: Was it Everything I Expected?

Scott Manley · 16:59

would do do a number on those air solar panels.

He Was THAT Good NFL Moments!

NFL Throwback · 27:44

Oh, is he going to do a number on the crowd here?

Peptide Expert: What Do Peptides Actually Do? (EXPLAINED) - Dr Alex Tatem

The Diary Of A CEO · 75:30

Turns out not eating or sleeping for 5 years will do a number on you, you know.

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